STUDY OF TRITERPENE COMPOUNDS IN SHOOTS OF CRATAEGUS ALMAATENSIS POJARK

Authors

  • Nadira Begim Kursanovna Zhalalova Candidate of Pharmaceutical Sciences, Lecturer at the Department of Pharmacognosy and Chemistry of Medicines, KSMA named after I.K. Akhunbaeva
  • Natalia Vladimirovna Kudashkina Doctor of Pharmaceutical Sciences, Professor, Dean of the Faculty of Pharmacy, Head of the Department of Pharmacognosy with a course of botany and fundamentals of herbal medicine, Bashkir State Medical University
  • Svetlana Rashitovna Khasanova Doctor of Pharmaceutical Sciences, Professor, Head of Practice, Faculty of Pharmacy, Department of Pharmacognosy with a course of botany and fundamentals of herbal medicine, Bashkir State Medical University
  • Anarbu Djaparovnа Muratalieva Candidate of Pharmaceutical Sciences, Head of Department Pharmacognosy and chemistry of drugs Kyrgyz State Medical Academy named after I.K. Akhunbaeva

Keywords:

shoots, Alma-Ata hawthorn, thin layer chromatography, spectrophotometry, triterpene compounds, ursolic acid.

Abstract

The study of saponins, the results of the qualitative and quantitative content of
triterpene compounds in the shoots of Alma-Ata hawthorn was carried out. The presence of
triterpene compounds in the studied raw material was established using thin layer chromatography.
The quantitative content of the sum of triterpene compounds was determined by spectrophotometry.
As a result of qualitative reactions, triterpene saponins were found. After hydrolysis in the system:
glacial acetic acid - hydrochloric acid - purified water (3.5: 1: 5.5) by thin layer chromatography,
the sum of saponins was separated in the chloroform-methanol-water system (18: 11: 2.7). Ursolic
acid was identified by spectrophotometry after the reaction of saponins with concentrated sulfuric
acid at 317 nm, which in terms of conversion was 1.33%.

References

Деканосидзе Г.Е., Чирва В.Я., Сергиенко Т.В. Биологическая роль, распространение и

химическое строение тритерпеновых гликозидов. Тбилиси. 1984. 348 с.

Копейка В.И. Семейный справочник лекарственных растений. Донецк: ООО «ПКФ

БАО» 2009. 224 с.

Тихонов В.Н., Калинкина Г.И., Сальникова Е.Н. Лекарственные растения, сырье и

фитопрепараты: Учеб.пособие / Под ред. С.Е. Дмитрука. Ч. 1. Томск. 2004. 116 с.

Государственная фармакопея Российской Федерации XIV издания. Том I. 1814 c. /

http://www.femb.ru/femb/pharmacopea.php

Кондратова Ю.А., Самофалова О.С., Артюшенко Е.А. Тритерпеновые соединения

вероники австрийской // Материалы 74-й межвуз. итог. науч. конф. студентов и молодых

ученых, посвящ. году молодежи в России «Молодежная наука и современность» (Курск,

−22 апреля 2009 г.). В 3-х частях. Курск. 2009. Ч. 2. С. 182−183.

Самылина И.А., Северцева В.А. Лекарственные растения Государственной фармакопеи.

М.: АНМИ. 2003. 534 с

Латыпова Г.М., Бубенчикова В.Н., Катаев В.А. Содержание урсоловой кислоты в

растениях рода первоцвет // Фармация. 2015. № 4. С. 21−24.

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Published

2023-12-19

Issue

No. 7 (2023): ИЗВЕСТИЯ НАЦИОНАЛЬНОЙ АКАДЕМИИ НАУК КЫРГЫЗСКОЙ РЕСПУБЛИКИ

Section

Phytotechnology

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