ARTEMISIA ANNUA AS A SOURCE OF BIOLOGICALLY ACTIVE SUBSTANCES OF PHENOLIC NATURE

Authors

  • A.G. Shutova State Scientific Institution «Central Botanical Garden of the National Academy of Sciences of Belarus»
  • N.A. Matveeva Institute of Cell Biology and Genetic Engineering of the National Academy of Sciences of Ukraine
  • V. Dupliy Institute of Cell Biology and Genetic Engineering of the National Academy of Sciences of Ukraine
  • Ya. Ratushnyak Institute of Cell Biology and Genetic Engineering of the National Academy of Sciences of Ukraine
  • P.S. Shabunya Institute of Bioorganic Chemistry
  • С.А. Fatykhova Institute of Bioorganic Chemistry

Keywords:

Artemisia annua L., “hairy” roots, hydroxycinnamic acids, extraction, ultrasonic treatment.

Abstract

The composition of phenolic compounds from samples of the above-ground mass
collected during the flowering period and the lines of transformed roots of Artemisia annua L.
was analyzed. The efficiency of bioactive compounds extraction using ultrasonic and microwave
treatment at different duration and temperature of the process was evaluated. The chemical
composition, in particular, the content of caffeylquinic acids and their derivatives as the main
active substances in the extracts of wormwood were determined by liquid chromatography with
mass-selective and diode-array detectors.

References

Daddy N.B., Kalisya L.M., Bagire P.G., Watt R.L., Towler M. J., Weathers P.J. (2017). Phytomedicine

: international journal of phytotherapy and phytopharmacology, 2017. 32, 37–40.

Nair M.S., Huang Y., Fidock D.A., Polyak S.J., Wagoner J., Towler M.J., Weathers P.J. (2021).

Journal of ethnopharmacology, 2021. 274, 114016.

Mirbehbahani F.S., Hejazi F., Najmoddin N., Asefnejad A. Progress in biomaterials, 2020. 9(3), 139–151.

Uozumi N. Adv Biochem Eng Biotechnol., 2004. 91, 75-103.

Srivastava S., Srivastava A.K. Crit Rev Biotechnol, 2007 .27 (1): 29-43.

Balasubramanian M., Anbumegala M., Surendran R., Arun M., Shanmugam G. Biotech., 2018. 8 (2), 128.

Ikawa M., Schaper T.D., Dollard C.A., Sasner J.J. J. Agric. Food Chem., 2003. 515, 1811–1813.

Косман В.М., Зенкевич И.Г. Растительные ресурсы, 2001. 37 (4), 123–129.

Государственная фармакопея Республики Беларусь. В 2 томах. Минск. 2012. 1. 201.

Published

2022-10-12