KINETICS AND MECHANISM OF INTERACTION OF ANESTHESIN AND PYRIDOXAL HYDROCHLORIDE AND GLUCOSE
Keywords:
vitamin B6, anesthesin, Schift base, N-glycosylamines, glucose.Abstract
The kinetics and mechanism of the reacions of anesthesin with pyridoxal and
glucose were studied. Under comparable conditions, the condensation of anesthesin with
pyridoxal and glucose includes two kinetically different steps. The first fast step is addition of the
anesthesin to pyridoxal and glucose with of the corresponding amino alcohol, the second (slower)
step is dehydration of the amino alcohol to give Schift base and N-glycosylamines. The scheme
of anesthesin with pyridoxal and glucose is proposed.
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